Important research perspectives are opened by the identification of functional markers that play a causative role in the development and progression of human colorectal cancer and which are targets or able to favour the activity of anticancer agents. Among the putative prognostic markers recently proposed, considerable attention has been received by the synchronous expression of more than one gene products. In ths article, we review a panel of immunohistochemical markers the prognostic value of which was evaluated in patients with colorectal neoplasms.

Key words: Immunohistochemistry, colorectal neoplasia, prognosis.

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