Apocrine ductal adenoma of the breast:
a problem of differential diagnosis
O. Tzaida1, G. Xepapadakis2,
E. Kirkou1, G. Asimakopoulos2
1Pathology Department
2Surgical Breast Clinic
A case of ductal adenoma of the breast with apocrine morphology,
in a 51 year old woman, is presented. The lesion a circumscribed
painful nodule of 2,5 cm accompanied by nipple discharge, was
considered suspicious of malignancy at the clinical and laboratory
preoperative investigation (mammography, fine needle aspiration).
The same ambiguous feature was observed at frozen section examination.
The real nature of the tumor as a benign neoplasm and its precise
classification was apparent at the histologic study and by immunohistochemical
findings. The correct identification of this unusual mammary neoplasm
minimize the danger of confusion with carcinoma, avoiding of
an inappropriate mastectomy.
Key words: Breast, ductal adenoma, apocrine change.
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