Hepatocypte transplantation
Morphology: Capabilities and Limitations
Demonakou-Vatopoulou M.
Pathology Department Sismanoglion G. H. Marousi Athens Greece
Interest in hepatocyte transplantation has increased widely in recent years.
Transplanting hepatocytes could be useful both for supporting
acute liver failure and for correcting genetic disorders. Morphology
of ectopically localized hepatocytes is the subject of continuing
study. The fate of intrasplenically transplanted hepatocytes has
been studied more extensively but experience for the fate in various
other sites is limited. Structural changes were well described,
but there are limitations to indefinite survival, appropriate
function and rejection.
Key words: Hepatocyte, transplantation, morphology.
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