Pituitary adenoma with appearance of nassal polyp
Giannou P.1, Kontogeorgos G.1, Elemenoglou J.3, Vamvassakis E.4, Rologis D.2, Orphanidis G.2
1Department of Pathology and 2Neurosurgical Clinic District General Hospital of Athens, 3Department of Pathology "Tzanion" General Hospital of Piraeus and 4Laboratory of Anatomy, University of Athens, Greece
Infiltration of the nasal mucosa by pituitary adenoma is uncommon and polypoid projection into the nasal cavity, is only infrequently encountered. An unusual case of a pituitary adenoma presented as nasal polyp in a 51-yrs-old patient with rhinorrhea is discussed. The tumor showed focal immunoreactivity for gonadotrophins (FSH and LH) and prolactin, and ultrastructurally had the morpology of a null cell, partly oncocytic adenoma associated with glycoprotein production. The differential diagnosis from other nasal tumors is discussed, and a brief review of the relevant literature is presented.
Key words: adenoma, immunohistochemistry, pituitary, nasal polyp, ultrastructure.
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